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At around 7 days seven in utero, the sex-relevant gene about the Y chromosome initiates the development in the testicles in male infants. The testicles create testosterone.
在青春期时,睾酮会令孩童出现第一种雄激素上升可见的现象。这些现象包括:[来源请求]
Testosterone has numerous main actions. It offers negative responses inhibition around the secretion of gonadotropin-releasing hormone with the hypothalamus along with the secretion of luteinizing hormone with the pituitary gland. In addition, it directs the event of your embryonic Wolffian ducts in to the vas deferens (ductus deferens) and seminal vesicles and stimulates the formation of muscle and bone.
利用睪酮的男性化作用,跨性别男性(即由女性經由變性成為男性)會以睪酮作為替代,以維持至一般正常男性的睪酮水平。同樣地,跨性别女性會使用藥物抑制睪酮的生成,以讓雌激素發揮效用。
放射免疫测定法:睾酮主要产生于睾丸小叶曲精管之间的间质细胞,此外肾上腺皮质也能合成。当标本中加入H睾酮和睾酮抗体即产生竞争抑制作用,在反应系统中,当H睾酮和其抗体量保持恒定,则标记抗体复合物的形成量受未标记抗原量所制约,用葡聚糖加膜活性炭进行分离,使结合标记抗原与游离标记抗原分开,测定沉淀的结合部分,进行液闪仪计数(dpm)与标准相比,求出未知样品的含量。
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Adult testosterone consequences are more clearly demonstrable in males than in females, but are probable vital that you both sexes. A few of these outcomes may well decrease as testosterone ranges could lessen within the later on many years of adult daily life.[36]
虽然雄性激素常被认为仅是男性的性激素,但女性亦会产生雄性激素,只是数量较低,负责性欲与性唤起。雄性激素也是男女体内雌性激素的前体。
過度超量或是長期的使用睪酮,會導致睪丸及男性生殖器萎縮,且導致永久性的陽痿。如果為女性,則會出現乳房萎縮、刺激毛髮過度生長、陰蒂肥大貌似小陰莖和长胡子等種種男性化現象。
Testosterone is answerable for a lot of the adjustments found in youngsters assigned male at delivery in the course of puberty, which includes:
Complete testosterone blood examination (this is often carried out in the morning since testosterone levels are maximum then).
在其他脊索動物的組織內也會有雄激素受體,而雄性及雌性對睪酮的反應也相當一致。在出生前雄性與雌性的睪酮劑量的差異,會導致在青春期或整個生命上的生物差異。
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Sexual arousal and masturbation in women make smaller improves in testosterone concentrations.[sixty five] The plasma concentrations of assorted steroids noticeably increase following masturbation in Guys as Special Deal well as the testosterone amounts correlate to Individuals amounts.[66]